“Calculus dissolution based oral rinse like Periogen® (Periogen Company-USA) with key ingredients of Tetrapotassium Pyrophosphate (TKPP), Sodium Tripolyphosphate (STPP), Sodium Bicrbonate, Sodium Fluoride and Citric Acid seems to be potential oral rinse for suppressing the mineralization of dental plaque when used on regular basis as an adjunct to tooth brushing”
“The results of the present study are intriguing and should be interpreted from a clinical perspective. Dentist/hygienists should prescribe anticalculus oral rinse (Periogen®) between the professionally cleaning of teeth. This could be a practice that would decrease the bio load in the oral cavity specially the new calculus deposits that serves as reservoir to dental plaque”
"A recently conducted clinical study proved that mouth rinse (Periogen®) containing tetrapotassium pyrophosphate and sodium tripolyphosphate as the anticalculus agent provides a clinically relevant reduction in calculus formation"
“Calculus dissolution based Periogen® mouthrinse provided clinically significant reduction in calculus formation in subjects with zirconium dioxide and titanium dental implants when used twice daily for 6 months as an adjunct to toothbrushing”
"Periogen effectively reduced the clinical symptoms of plaque-induced gingivitis, and had a statistically significant effect on the reduction of clinical and salivary concentration parameters when compared to 0.12% Chlorhexidine."